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. 2020 Sep 3;10:14543. doi: 10.1038/s41598-020-71429-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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DC₅₀ values (μM) for the 22_TERRA (upper panel) and 26_ds (middle panel) determined by FID upon addition of the metallohelices in 10 mM potassium phosphate buffer (pH 7) and various concentrations of KCl. Binding selectivity (lower panel) was calculated as a ratio between DC₅₀ values for the 26_ds and the 22_TERRA. Data shown are expressed as the mean of two independent experiments; error bars indicate the standard error of the mean. Symbols (*, **, ***) and (ns) at the top of the bars indicate statistically significant difference (p ≤ 0.1, p ≤ 0.05, p ≤ 0.01) and statistically insignificant difference (p > 0.1), respectively.