| AE | adverse event |
| AUC | area under the curve |
| bpm | beats per minute |
| Cmax | maximum plasma concentration |
| CI | confidence interval |
| C-QTc | corrected concentration-QT interval |
| CV% | coefficient of variance |
| hERG | Human Ether-à-go-go-Related Gene |
| ICH E14 | International Conference on Harmonization E14 guidance |
| PK | pharmacokinetics |
| QTcF | Fridericia corrected QT interval |
| ΔQTcF | Baseline adjusted Fridericia-corrected QTc |
| ΔΔQTcF | Baseline and placebo adjusted Fridericia-corrected QTc |
| TEAE | treatment emergent adverse event |
| tmax | time at Cmax |
| TTX | tetrodotoxin |
| VGSC | voltage-gated sodium channel |
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