Table 1.
Genes targeted by commercial HSV typing assays.
| Test | Manufacturer | HSV-1 Target | HSV-2 Target | Site of Known HSV-1 x HSV-2 Recombination Event? | ||
|---|---|---|---|---|---|---|
| Gene | Protein Product | Gene | Protein Product | |||
| Aptima | Hologic, Inc. | UL42 | DNA Polymerase Processivity Subunit | UL42 | DNA Polymerase Processivity Subunit | No |
| Aries | Luminex Corporation | Not Available | Not Available | NA | ||
| IsoAmp | BioHelix Corporation | UL27 | Glycoprotein B | UL27 | Glycoprotein B | Yes |
| MultiCode-RTx | EraGen Biosciences, Inc. | UL27 | Glycoprotein B | UL27 | Glycoprotein B | Yes |
| BD ProbeTec | BD Diagnostic Systems | Not Available | Not Available | NA | ||
| Simplexa | Focus Diagnostics | UL30 | DNA Polymerase | UL30 | DNA Polymerase | Yes |
| Amiplivue | Quidel Corporation | Not Available | Not Available | NA | ||
| IMDX | Intelligent Medical | US6 | Glycoprotein D | UL30 | DNA Polymerase | Yes (UL30) |
| Solana | Quidel Corporation | US7 | Glycoprotein I | Intergenic between UL47 and UL48 | Intergenic between VP13/14 and VP16 | Yes (Intergenic between UL47 and UL48) |
| Artus | Qiagen | UL30, US6 | DNA Polymerase, Glycoprotein D | UL30, US6 | DNA Polymerase, Glycoprotein D | Yes (UL30) |
| SeeGene Anyplex | SeeGene | US6 | Glycoprotein D | US6 | Glycoprotein D | No |
| Quidel Molecular Direct | Diagnostic Hybrids | US4 | Glycoprotein G | US4 | Glycoprotein G | No |
| Sentosa | Vela Diagnostics | UL30 | DNA Polymerase | UL30 | DNA Polymerase | Yes |
| Elite MGB Ingenius | Elitechgroup | US6 | Glycoprotein D | US4 | Glycoprotein G | No |