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Pyrimidine addition counteracts the antiviral activity of DHODH inhibitors. A549 cells were treated with the indicated DHODH inhibitors (5 µM) and with or without uridine (A) or cytidine (B) and infected (MOI = 0.01) with rCL-13/ZsG. At 48 h pi, ZsG expression levels were determined. Values correspond to four independent replicates. Error bars represent mean +/− SEM. Statistical significance was calculated by ANOVA (**** p < 0.00001).
