TABLE 1.
Analysis of activation of the ρ1 receptor by GABA
The table gives the results of fitting the GABA conc.-Popen response data to eq. 1. The first column shows the constrained value of Popen at 10 μM GABA. The next columns show the calculated value of L and the fitted values of KC and c (best-fit parameter ± S.D.). The number of binding sites for GABA was constrained to 5.
| Popen at 10 μM GABA | L | KC (μM) | c |
|---|---|---|---|
| 0.999 | 1018 | 2.11 ± 0.46 | 0.085 ± 0.012 |
| 0.98 | 1039 | 1.73 ± 0.33 | 0.097 ± 0.011 |
| 0.96 | 1060 | 1.44 ± 0.26 | 0.110 ± 0.010 |
| 0.94 | 1083 | 1.24 ± 0.21 | 0.119 ± 0.010 |
| 0.92 | 1106 | 1.09 ± 0.19 | 0.128 ± 0.009 |