Table 3.
Main Data | Tacket et al. 1984 [48] | Lonati et al. 2015 [50] | ||||
---|---|---|---|---|---|---|
Study Period | 1973–1980 | 2007–2013 | ||||
BoNT Involved | Bont A | BoNT B (63%), BoNT A (9%), BoNT BF (2%), BoNT AB (1%); not Identified in 25% of Cases | ||||
n° of patients | 134 | 98 | ||||
n° of patients treated with antidote | no antidote | n° of patients treated with antidote | no antidote | |||
115 (87%) | 17 (13%) | 59 (60%) | 39 (40%) | |||
time of antidote administration | <24 h | >24 h | – | <24 h | >24 h | – |
orotracheal intubation (OTI) | n.a. | n.a. | n.a. | 26% | 53.8% | 7.6% |
duration of OTI (days) |
n.a. | n.a. | n.a. | 13.6 ± 5.6 | 21 ± 15.5 | n.a. |
median hospital stay (days) | 10 | 41 | 56 | n.a. | n.a. | n.a. |
fatality rate | 10% | 15% | 46% | 0% | 1% * | 0% |
note: * BoNT-B, female 89-year-old, severe comorbidity. n.a.: not available.