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. 2020 Jul 31;12(8):842. doi: 10.3390/v12080842

Figure 1.

Figure 1

Cartoons depicting HIV-1 Gag MA-HBR, and PI(4,5)P2. (a) Schematic illustration of HIV-1 Gag with the structure of HIV-1 MA (PDB accession number 2HMX) showing the basic residues of the MA-HBR in blue. The key basic residues studied in detail in our recent work [48] are indicated (in the nomenclature for MA amino acid residues used in this review, the first methionine removed upon myristylation is not counted). (b) Illustration of 38:4 PI(4,5)P2, the predominant molecular species of PI(4,5)P2 in many primary mammalian cells [49,50,51,52,53].