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. 2020 Aug 6;12(8):504. doi: 10.3390/toxins12080504

Table 5.

Intestinal morphology and Ki-67 1 proportion in histology sections of mid jejunum in newly-weaned pigs fed diets high (HM) or low (LM) in mycotoxins 2 or postbiotic yeast cell wall-based blend (PYCW) for 36 days.

Diet LM HM SEM p Value
PYCW 0% 0.2% 0% 0.2% Diet PYCW Diet vs. PYCW
Villus width, µm 420.9 432.4 401.9 407.7 7.1 0.263 0.684 0.611
Villus height (V), µm 153.2 157.7 161.2 160.7 19.8 0.100 0.512 0.826
Crypt depth (C), µm 214.0 223.4 203.4 203.5 11.6 0.045 0.522 0.527
V:C 2.00 1.97 2.02 2.04 0.14 0.651 0.932 0.785
Ki-67 proportion, % 25.93 25.61 27.27 27.44 2.40 0.343 0.963 0.882

1 Ki-67 is an estimate of the proliferative rate, calculated based on the proportion of cells positive to Ki-67 staining (immunohistochemistry) to the total number of cells in the crypt. 2 HM has 1.0 μg/kg of AFB1 and 2258 μg/kg of DON on average for phases 1 and 2, and 44.6 μg/kg of AFB1 and 4635 μg/kg of DON for phase 3.