Table 4.
Peptides | Microorganisms | MIC (µM) | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NaCl (mM) | MgCl2 (mM) | pH | Temperature (°C) | Serum (10%) | ||||||||||
50 | 100 | 150 | 0.5 | 1 | 2 | 6 | 7 | 8 | 100 | 75 | 50 | |||
Brevinin-1OS | S. aureus | 8 | 8 | 8 | 4 | 8 | 8 | 8 | 4 | 4 | 4 | 4 | 4 | 4 |
MRSA | 8 | 16 | 32 | 16 | 16 | 16 | 64 | 8 | 4 | 16 | 16 | 16 | 8 | |
E. faecalis | 32 | 32 | 64 | 32 | 32 | 32 | 128 | 32 | 16 | 16 | 16 | 16 | 16 | |
C. albicans | 32 | 32 | 32 | 16 | 16 | 16 | 64 | 16 | 16 | 16 | 16 | 16 | 8 | |
E. coli | 64 | 64 | 64 | 128 | 128 | 128 | 32 | 32 | 128 | 64 | 64 | 64 | 256 | |
P. aeruginosa | >512 | >512 | >512 | >512 | >512 | >512 | 128 | 256 | 256 | 256 | 256 | 256 | >512 | |
OSd | S. aureus | 128 | 256 | 256 | 128 | 128 | 256 | 64 | 32 | 32 | 32 | 32 | 32 | 128 |
MRSA | 512 | 512 | 512 | 512 | 512 | 512 | 256 | 128 | 64 | 128 | 64 | 64 | 128 | |
E. faecalis | 512 | 512 | 512 | 512 | 512 | 512 | 256 | 128 | 128 | 256 | 256 | 256 | >512 | |
C. albicans | 128 | 128 | 256 | 64 | 64 | 128 | 64 | 32 | 32 | 128 | 32 | 32 | 64 | |
E. coli | 256 | 256 | 512 | 128 | 256 | 512 | 64 | 64 | 64 | 256 | 64 | 64 | 128 | |
P. aeruginosa | 256 | 512 | 512 | 256 | 256 | 256 | 128 | 128 | 64 | 128 | 64 | 64 | 256 | |
OSe | S. aureus | 16 | 16 | 16 | 16 | 16 | 16 | 16 | 8 | 4 | 8 | 8 | 8 | 32 |
MRSA | 16 | 16 | 32 | 16 | 16 | 32 | 64 | 16 | 8 | 16 | 16 | 16 | 64 | |
E. faecalis | 64 | 64 | 64 | 64 | 64 | 64 | 32 | 64 | 32 | 64 | 64 | 64 | 128 | |
C. albicans | 16 | 16 | 16 | 8 | 8 | 16 | 16 | 8 | 4 | 8 | 8 | 8 | 16 | |
E. coli | 32 | 32 | 32 | 16 | 64 | 64 | 32 | 16 | 16 | 16 | 16 | 16 | 64 | |
P. aeruginosa | 64 | 64 | 128 | 64 | 64 | 128 | 32 | 64 | 32 | 32 | 32 | 32 | 128 | |
OSf | S. aureus | 64 | 64 | 64 | 64 | 64 | 64 | 128 | 8 | 16 | 8 | 8 | 8 | 32 |
MRSA | 128 | 256 | 256 | 128 | 128 | 256 | 512 | 16 | 32 | 32 | 16 | 16 | 64 | |
E. faecalis | 256 | 256 | 512 | 256 | 256 | 256 | 512 | 32 | 128 | 32 | 32 | 32 | 128 | |
C. albicans | 64 | 64 | 128 | 32 | 64 | 64 | 128 | 8 | 16 | 16 | 8 | 8 | 32 | |
E. coli | 64 | 128 | 128 | 128 | 128 | 256 | 128 | 8 | 32 | 16 | 8 | 8 | 32 | |
P. aeruginosa | 128 | 256 | 256 | 128 | 256 | 256 | 128 | 256 | 64 | 64 | 64 | 64 | 64 |