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. 2020 Aug 11;42(1):799–806. doi: 10.1080/0886022X.2020.1803085

Table 4.

Laboratory data before the prescription of phosphate binders, stratified according to the presence or absence of a PPI.

  LC
FCH
SFOH
Without PPI (n = 9) With PPI (n = 10) p-value Without PPI (n = 7) With PPI (n = 20) p-value Without PPI (n = 7) With PPI (n = 18) p-value
Hemoglobin (g/dl) 11.2 ± 0.5 11.6 ± 0.9 0.300a 11.2 ± 0.8 11.0 ± 0.9 0.713a 11.2 ± 0.7 11.1 ± 0.7 0.553a
Albumin (g/dl) 3.6 ± 0.3 3.6 ± 0.3 0.928a 3.9 (3.7–3.9) 3.6 (3.4–3.7) 0.127b 3.8 ± 0.2 3.5 ± 0.2 0.006a
Urea nitrogen (mg/dl) 78 ± 11 69 ± 11 0.079a 68 ± 9 62 ± 13 0.259a 72 ± 15 70 ± 14 0.766a
Creatinine (mg/dl) 12.0 ± 2.6 10.1 ± 2.1 0.098a 12.3 ± 2.8 12.2 ± 2.7 0.905a 12.2 (12.0–15.0) 10.7 (9.6–11.5) 0.065b
Calcium (mg/dl) 9.1 (8.2–9.7) 8.6 (8.3–8.9) 0.462b 8.8 (8.7–9.6) 8.9 (8.7–9.3) 0.698b 8.5 ± 0.6 8.8 ± 0.6 0.296a
Phosphate (mg/dl) 6.7 ± 0.9 6.3 ± 1.0 0.341a 6.4 ± 0.8 6.8 ± 1.2 0.432a 6.6 ± 0.4 6.7 ± 0.7 0.550a
Parathyroid hormone (pg/ml) 253 ± 101 281 ± 171 0.665a 182 ± 90 250 ± 136 0.238a 426 (305–545) 257 (169–359) 0.053b
Phosphate, average (mg/dl) 6.1 ± 0.7 5.7 ± 0.8 0.330a 5.7 (5.4–5.8) 6.0 (5.7–6.4) 0.056b 6.2 ± 0.4 6.2 ± 0.6 0.894a

Uncorrected serum calcium levels are shown. The phosphate average means the average of pre-dialysis serum phosphate levels during the 3 months before the prescription of the phosphate binder.

aUnpaired t-test.

bMann–Whitney rank-sum test.