Table 4.

Effectiveness of hypnotic medicines over time

	< 12 h	12–24 h	24–36 h	> 48 h
Zolpidem	WMD − 0.1 CI − 0.39 to 0.19 p value < 0.01	WMD − 0.3 CI − 0.38 to − 0.22 p value < 0.01	WMD − 1.49 CI − 1.63 to − 1.34 p value < 0.01	WMD − 1.09 CI − 1.12 to − 1.06 p value < 0.01
Melatonin	WMD 1.09 CI 0.77 to 1.40 p value < 0.01	WMD 0.50 CI 0.18 to 0.82 p value < 0.01	n/a	n/a
Midazolam	WMD − 0.32 CI − 0.38 to − 0.27 p value < 0.01	WMD 0.20 CI − 0.14 to 0.54 p value < 0.01	WMD 1.39 CI 1.05 to 1.72 p value < 0.01	n/a
Lorazepam	WMD 1.00 CI 0.88 to 1.12 p value < 0.01	n/a	n/a	n/a

WMD weighted mean difference, CI confidence interval, n/a no measure for this time point