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. 2020 Aug 21;11:1301. doi: 10.3389/fphar.2020.01301

Figure 6.

Figure 6

Effect of Obeth from O. bracteata on histology of liver tissues as assessed by H & E staining. (A) Control group (tap water ad libitum) (GI) showing normal lobular architecture with clear portal triad. (B) CCl4: Olive oil (1:1; 1mL kg-1b.wt.) induced necro-inflammatory activity in GII was noted. Treatment of Obeth extract was associated with diminution of portal hypertension with increasing dose. (C) Silymarin (100 mg kg-1b.wt.) + CCl4, (D) low dose (50 mg kg-1b.wt.) + CCl4, (E) medium dose (100 mg kg-1b.wt.) + CCl4, (F) High dose (200 mg kg-1b.wt.) + CCl4, (G) Negative (only extract 100 mg kg-1b.wt. Arrows indicate Kupffer cell (KC), central vein (CV), hepatic cells (HC), blood sinusoids (BS), steatosis (S) (black arrow), and necrosis (N) (red arrow).