Table 3.

List of differentially regulated proteins in 5-FU treated group vs control group. Positive fold-change value denotes up-accumulation and negative fold change value denotes down-accumulation in comparison with control.

Gene symbol	Protein name	P-value (FDR)	Fold change (log2 vs control)	Biological process
Apoa2	Apolipoprotein A-II	0.004158	0.771235	Lipid transport and metabolism, retinoid transport, chylomicron remodeling
Mt-1	Metallothionein-1	0.012015	0.674153	Cellular metal ion homeostasis, nitric oxide mediated signal transduction
Ptma	Prothymosin alpha	0.016023	0.518607	Histone exchange, negative regulation of apoptotic process, cell cycle
Ces1c	Carboxylesterase 1C	0.023659	0.4521	Lipid catabolic process, response to metal ions
Rpl29	60S ribosomal protein L29	0.006359	0.429547	Translation
Cavin2	Caveolae-associated protein 2	0.021712	0.404603	Transcription regulation, lipid metabolism
Cdk11b	Cyclin-dependent kinase 11B	0.013975	0.377805	Cell cycle
Dnajc3	DnaJ homolog subfamily C member 3	0.013975	0.377805	Stress response, translation regulation, unfolded protein response
Ipo7	Importin-7	0.048261	0.316322	Innate immune response, protein import into nucleus
S100a9	Protein S100-A9	0.037099	-1.70807	Apoptosis, autophagy, chemotaxis, immunity, inflammatory response, innate immunity
Anxa5	Annexin A5	0.02236	-0.74139	Calcium ion transmembrane transport, apoptosis