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. 2020 Aug 21;11:1030. doi: 10.3389/fphys.2020.01030

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Copyright © 2020 Wu, Wu, Guo, Pluimer and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Flowchart of article selection. Identification through PubMed searches yielded 232 articles related to blood–brain barrier (BBB) and vascular impairment in mild traumatic brain injury (mTBI) published during 2010–2020, which were further screened. Based on abstract and eligibility, 215 articles were excluded, and a total of 17 original research articles with BBB dysfunction in murine models of mTBI were determined by full-text examination and included in the review.