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Structure of mannose receptor (MR). Graphical depiction of the domains of MR and the ligands bound by each domain. CRD = cysteine rich domain, which binds sulfonated sugars. FNII = fibronectin type II domain, which binds collagen. C-type lectin domains = calcium-dependent domains that have been demonstrated to bind mannose, fucose, and N-acetylglucosamine.
