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. 2020 Aug 21;11:863. doi: 10.3389/fpsyt.2020.00863

Figure 1.

Figure 1

Schematic images from psychiatric research implementing the SQUID-MEG system. (A) SQUID-MEG system: the brain is covered by fixed positional sensors in the dewar helmet. (B) A representative, frequently-employed auditory stimulation paradigm for MEG diagnosis, including the MMN (left) and ASSR (right) responses. (C) Orthodox MEG analysis: a sensor-level analysis making a comparison between patients with SZ (red) and HC (blue) (left) and dipole analysis (right). (D) The current method used in MEG psychiatric research, from right side: accurate MEG-MRI co-registration using a 3D laser scanner (13), specified ROI and source reconstruction results using MNE, and time-frequency analysis using source waveforms; induced power (upper) and the phase-locking factor (lower). SQUID, superconducting quantum interference device; SZ, schizophrenia; HC, healthy control; MMN, mismatch negativity; ASSR, auditory steady-state response; ROI, region of interest; MNE, minimum norm estimates.