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. 2020 Aug 21;11:863. doi: 10.3389/fpsyt.2020.00863

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Copyright © 2020 Hironaga, Takei, Mitsudo, Kimura and Hirano

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Potential application of the OPM-MEG system in future work. (A) Newly developed system and principle of atom magnetometer (upper panel). Two laser beams are arranged orthogonally; one is the pump beam that polarizes the vaporized atomic electron spin, and the other is the probe beam that measures the state of spin evolving in the magnetic field B. Rb denotes rubidium atom. The lower sub-figure presents a pediatric OPM-MEG system adapted from Hill et al. (14). (B) RSN analysis will involve deep brain structures. Representative RSNs (left) and an image showing graph theory analysis (right) (15). (C) The cortico-subcortical network could be targeted in future work. Thalamocortical communication (upper left) and the basal ganglia loop, 1. cortex→2. striatum (a. caudate nucleus orb. putamen)→3. pallidum→4. thalamus→1.cortex (lower right). OPM, optically pumped magnetometers; TRN, thalamic reticular nucleus.