Table 1.
Patients and samples characteristics.
| Breast cancer carriers | Non cancer women | p | |
|---|---|---|---|
| N | 43 | 6 | |
| Age (median) (range), mean (sd) | 67.5 (40–93); 67 (13.3) | 47 (26–51); 43.4 (9.0) | 10−4 |
| BMI (median) (range), mean (sd) | 27.5 (19.1–38.2); 27.8 (5.2) | 25.1 (21–29.6); 25.2 (4.5) | 0.33 |
| Family history of breast cancer | 10/43 (23.2%) | 3/6 (50%) | |
| Age at menarche (med) | 13 (10–17) | 13 (11–14) | |
| Menopausal | 32/43 (74.4%) | 0 | |
| Taking exogenous hormones at diagnosis (pill or HRT) | 13/43 (30.2%) | 0 | |
| History of previous breast biopsy | 12/43 (27.9%) | 1 | |
| Diabetes | 8/43 (18.6%) | 0 | |
| Dyslipidemia | 15/43 (34.9%) | 0 | |
| Vascular disease | 7/43 (16.3%) | 0 | |
| Current smoker | 5/43 (11.6%) | 2 | |
| Type of cancer | – | ||
| DCIS | 2,00 | – | |
| Invasive | 41,00 | – | |
| ER expression | 29/43 (67.4%) | – | |
| PR expression | 27/43 (62.8%) | – | |
| HER2 overexpression or amplification | 2/43 (4.6%) | – | |
| Node-positivity | 13/43 (30.2%) | – | |
| Type of breast surgery | – | ||
| Lumpectomy | 31/43 (72.1%) | 5/5 (100%) | |
| Mastectomy | 11/43 (25.6%) | – |
p = Welsch test.