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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Gastroenterology. 2019 Nov 20;158(4):1044–1057.e17. doi: 10.1053/j.gastro.2019.11.025

Figure 5.

Figure 5.

Putative miRNA regulation of the dynamic transcriptome of repopulating hepatocytes. (A) Transcripts from the Wang et al. data set were clustered by k-means partitioning into four groups. Black bars indicate group medians. (B) The 3’UTRs of cluster 4 mRNAs were significantly enriched for seed recognition sequences of several miRNAs identified as strong regulators of liver repopulation. (C) Density plots of 3’UTR GC content. Dashed vertical lines indicate population medians. Cluster 4 transcripts have significantly reduced GC content compared to clusters 1–3.