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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Trends Neurosci. 2020 Feb 7;43(3):144–154. doi: 10.1016/j.tins.2020.01.003

Figure 1: Function of the astrocyte-microglia module from homeostasis to pathology.

Figure 1:

Under physiologic conditions astrocytes (ochre) and microglia (blue) support neuronal functions, whereas in pathology they lose some of their supportive functions in favor of optimizing survival. This is accompanied by a change in morphology, secretome and increase in reactive markers and phagocytic activity.