Table 1.
Patient and tumour characteristics.
| Variables | Participants N = 65 | Non-Participants N = 86 | p-value |
|---|---|---|---|
| General patient characteristics | |||
| Age, mean in years (SD) | 72.8 (5.4) | 75.1 (5.7) | 0.01* |
| Gender, n (%) | |||
| Male | 42 (64.6) | 31 (36.0) | |
| Female | 23 (35.4) | 55 (64.0) | 0.00* |
| Nationality, n (%) | |||
| Dutch | 64 (98.5) | 81 (94.2) | 0.24 |
| Domains of frailty | |||
| Somatic - Comorbidity | |||
| ASA-classification,n (%) | |||
| ASA 1–2 | 53 (81.5) | 49 (57.0) | |
| ASA 3–4 | 12 (18.5) | 37 (43.0) | 0.00* |
| Charlson Comorbidity Index, median (IQR) | 4.0 (2.0–6.0) | 3.0 (2.0–6.0) | 0.88 |
| Polypharmacy (≥ 4), n (%) | 28 (43.1) | 58 (67.4) | 0.00* |
| Nutritional status | |||
| BMI, mean (SD) | 26.9 (4.2) | 28.0 (6.0) | 0.18 |
| Social status | |||
| Marital status, n (%) | |||
| Married | 53 (81.5) | 50 (58.1) | |
| Widow(er) | 9 (13.9) | 24 (27.9) | |
| Divorced | 1 (1.5) | 5 (5.8) | |
| Single | 2 (3.1) | 7 (8.1) | 0.01* |
| Housing,n (%) | |||
| Independent, alone | 12 (18.8) | 33 (38.4) | |
| Independent, with others | 52 (81.3) | 51 (59.3) | |
| Nursing home | 0 | 2 (2.3) | 0.02* |
| Psychological status | |||
| Concerns about hospital admission, n (%) a | 17 (27.9) | 27 (34.2) | 0.47 |
| Anxiety that influences daily life, n (%) a | 4 (6.6) | 4 (5.1) | 0.73 |
| Use of psychiatric medication? n (%)b | 6 (9.8) | 8 (10.3) | 1.00 |
| Functional status | |||
| Impaired ADLc (Katz ≥1), n (%) | 4 (6.2) | 14 (16.7) | 0.05 |
| Participation in other research | |||
| - Yes, n (%) | 34 (52.3) | 39 (45.3) | 0.42 |
| Tumour characteristics | |||
| Tumour location,n (%) | |||
| Intracavitary | 54 (83.1) | 64 (74.4) | |
| Superficial | 11 (16.9) | 22 (25.6) | 0.20 |
| Primary Malignancy | |||
| Gastro-intestinal oncology d | 48 (73.8) | 53 (61.6) | |
| Gynaecological oncology e | 7 (10.8) | 19 (22.1) | |
| Other oncology f | 10 (15.4) | 14 (16.3) | 0.17 |
| Recurrent disease, yes, n (%) | 18 (27.7) | 35 (40.7) | 0.12 |
| Neoadjuvant therapy, yes, n (%) | 24 (36.9) | 36 (41.9) | 0.54 |
SD: standard deviation; ASA: American Society of Anesthesiologists [19]; BMI: body mass index; ADL: activities of daily living; ⁎Statistically significant, p < 0.05.
a
Data missing for four participants and seven non-participants.
b
Data missing for four participants and eight non-participants.
c
Data missing for two non-participants.
d
Mostly colorectal cancer (n = 77).
e
Vulva carcinoma (n = 20) and ovarium carcinoma (n = 6).
f
Mostly sarcoma (n = 12).