Table 2. Semi-quantitative scores of pathological lesions on five autopsied organs from challenged horses inoculated with three env diversity-varied strains, prior and post immunosuppressed.
| Stage | Group | Animal ID | Pathological changes score | ||||
|---|---|---|---|---|---|---|---|
| lung | liver | kidney | spleen | Lymph node | |||
| Immunocompetent | EIAV_HD | 2 | 0 | 2 | 1 | 0 | 0 |
| EIAV_MD | 13 | 2 | 1 | 2 | 2 | 1 | |
| EIAV_LD | 16 | 2 | 2 | 2 | 3 | 1 | |
| EIAV_LD | 9 | 3 | 1 | 1 | 3 | 3 | |
| EIAV_LD | 21 | 3 | 2 | 3 | 2 | 2 | |
| Immunosuppressed | EIAV_HD | 3 | 0 | 0 | 1 | 0 | 0 |
| EIAV_MD | 4 | 0 | 0 | 1 | 0 | 0 | |
| EIAV_LD | 6 | 0 | 0 | 0 | 1.5 | 0 | |
| EIAV_LD | 7 | 0.5 | 0 | 0.5 | 1.5 | 1 | |
| EIAV_LD | 11 | 0 | 0.5 | 0.5 | 0.5 | 0.5 | |
Note: Semi-quantitative scoring method was used to reflect the severity of organs from five immunocompetent horses and five immunosuppressed horses. “0” indicated a normal organ, “1” indicated mild pathological changes, “2” indicated moderate pathological changes and “3” indicated severe pathological changes.