Table 3. Viral shedding in COVID-19 patients with different severity.
| Variable | Value | P Value | ||
|---|---|---|---|---|
| Overall (n = 303) | Mild (n = 277) | Severe-critical (n = 26) | ||
| Time from onset to negative nucleic acid detection in pharyngeal swab—days | 8 (5–12) | 8 (5–11) | 16 (8–22.5) | <0.001 |
| Time from onset to negative nucleic acid detection in blood—days | 14 (10–18) | 13 (10–17) | 22.5 (16.5–30) | <0.001 |
| Time from onset to negative nucleic acid detection in urine—days | 8 (5–11) | 7 (5–10) | 12 (7–21) | <0.001 |
| Time from onset to negative nucleic acid detection in faeces—days | 10 (7–15) | 10 (7–13) | 21 (16.8–29) | <0.001 |
| Time from antiviral therapy to negative nucleic acid detection in pharyngeal swab—days | 2 (1–6) | 2 (1–6) | 11 (3.8–15.5) | <0.001 |
| Time from antiviral therapy to negative nucleic acid detection in blood—days | 9 (5–12) | 9 (2–11) | 19 (13.8–24) | <0.001 |
| Time from antiviral therapy to negative nucleic acid detection in urine—days | 2 (1–4) | 1 (1–4) | 6 (2–14.5) | <0.001 |
| Time from antiviral therapy to negative nucleic acid detection in faeces—days | 4 (2–10) | 4 (1–8) | 15.5 (11.5–20.8) | <0.001 |
Values are presented by median (interquartile range). Median values of mild and severe-critical cases are compared with Mann–Whitney U test.