Table 3.

FDR significant main effects of genetic variants on hippocampal subfield volume.

Gene	Probe	Chr	bp	Tested allele	CEU MAF	ASW MAF	Subfield	Beta discovery	Pval discovery	FDR qval discovery	PVE discovery	Beta replica-tion	Pval replica-tion
LINC02571	rs6906714	6	31270038	G	0.071	0.123	R-fimbria	15.73	5.99E-08	0.0056	0.1489	−0.517	0.8636
	rs17012755	2	76709646	A	0.061	0.098	R-fimbria	22.01	6.05E-08	0.0056	0.1479	1.988	0.6019
	rs76832471	2	211570988	G	0.096	0.09	log L-fimbria	−16.4	6.51E-08	0.0121	0.1462	−2.384	0.5432
	rs9499406	6	103816931	C	0.035	0.139	R-subiculum	−46.38	8.19E-08	0.0151	0.1082	6.916	0.2368
RBBP6	rs7196581	16	24552179	G	0.086	0.049	L-CA1	53.62	1.51E-07	0.0280	0.0964	−13.85	0.7599
TUNAR	rs12880795	14	96379833	T	0.525	0.27	L-HATA	4.743	3.43E-07	0.0372	0.1206	4.107	0.0004
LOC105376580	rs2553974	11	19238380	A†	0.318	0.582	L-HATA	4.88	4.02E-07	0.0372	0.1193	−0.4725	0.6168
ARMC6	rs73008928	19	19146729	T	0.061	0.016	R-HATA	9.609	2.33E-07	0.0424	0.1235	−1.5	0.6048
RBBP6	rs7196581	16	24552179	G	0.086	0.049	R-HATA	7.939	4.58E-07	0.0424	0.1165	1.307	0.5551
LINC01736	rs3811492	1	230142626	C	0.131	0.451	L-HATA	4.866	8.13E-07	0.0498	0.1136	1.212	0.2411

*Effect size for untransformed L-fimbria.

^†Tested allele in replication dataset is C.

PVE = proportion of variance in imaging phenotype explained by the SNP.