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DM increases systemic levels of inflammatory mediators in CL individuals. (A) LTB4, (B) PGE2, (C) TNF-a and (D) IL-6 levels in plasma of individuals with Cutaneous Leishmaniasis, without diabetes (CL) or with diabetes (CL + DM) measured by ELISA. CL, n = 8; CL + DM, n = 12. Data shown in median. Mann-Whitney test. *p < 0.05; **p < 0.01.
