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. 2020 Jun 11;9(1):1275–1286. doi: 10.1080/22221751.2020.1773744

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — DM individuals are more prone to CL infection. (A) Histological images of a representative CL (left) and CL + DM (right) lesions in HE (above) and IHQ (below). Quantification of neutrophils (B) and amastigotes for field (C) in the lesions of CL and CL + DM individuals. Expression of ALOX5 (D) and PTGS2 (E) in the lesion of CL and CL + DM individuals detected by RT-qPCR. Blue arrows: neutrophils; white arrows: amastigotes. Scale bar: 20 µm. 40x objective with 200% digital magnification in HE and 150% in IHQ. Data shown in median (B,C). Box and whiskers with min to max (D,E). Mann-Whitney test (B,D). Chi-squared test for trend (C). *p < 0.05; **p < 0.01.