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. 2020 Jun 11;9(1):1275–1286. doi: 10.1080/22221751.2020.1773744

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Monocyte-derived macrophages from individuals with CL + DM are more susceptible to Leishmania braziliensis. Representative images of cultured macrophages from CL and CL + DM individuals after L. braziliensis infection (A). Quantification of infection rate (B), amastigotes in 100 cells (C) and amastigotes per cell (D) in macrophages from CL and CL + DM individuals, after infection with L. braziliensis. (E) Spearman correlation between blood glucose levels and infection rate in the CL (open circles) and CL + DM (full circles). Arrows indicate the presence of amastigotes. Data shown in median. Mann-Whitney test (B-D). Spearman correlation (E). *p < 0.05; **p < 0.01.