Figure 7.
LTB4 production of monocyte-derived macrophages from CL + DM individuals is abolished after L. braziliensis infection. Production of LTB4 (A) and PGE2 (B) in the supernatant of cultured macrophages from CL and CL + DM individuals after infection with L. braziliensis. Ratio between PGE2 and LTB4 production in the supernatant of uninfected or infected macrophages (C). Graphical abstract (D). Data represent individual values before and after infection. Wilcoxon’s test and Kruskal-Wallis with Dunn’s post-test. *p < 0.05; **p < 0.01.