Table 4. Targets of pathogenic parasites for development of specific aptamers.
Type of parasites | Aptamer | Target | Method |
---|---|---|---|
Trypanosoma cruzi [11] | Apt68 | Mammalian stage trypomastigotes | Streptavidin paramagnetic beads coated with biotinylated Apt68 |
Leishmania [28] | LmWC-25R; LmHSP 7b/11R | Leishmania promastigote protein extracts | Fluorescent enzyme-linked DNA aptamer-magnetic bead sandwich assay |
Plasmodium for malaria [30] | P38 or NG3 | Plasmodium lactate dehydrogenase and plasmodium falciparum glutamate dehydrogenase | Dye coupled aptamer-captured enzyme catalysed reaction |