Table 1. Recommended drug treatment for Balamuthia mandrillaris encephalitis.

Drug	Dose	Route	Dutation
Amphotericin B liposome	0.1–0.5–1–1.5–2–2.5 mg/kg/day once daily.	IV	36 days
Amphotericin B	0.18–0.25–0.375–0.375–0.5 mg/kg/day once daily.	IV	5 days
Amphotericin B	0.025–0.05–0.075–0.1–0.2–0.4–0.5–0.6 mg every three days.	Intrathecal	8 days
TMP-SMX	30–36 mg/kg/day in two divided doses.	PO	24 days
Albendazole	400 mg once daily.	PO	16 days
Fluconazole	400 mg once daily.	IV	59 days
Fluorocytosine	100 mg/kg/day in four divided doses.	PO	48 days
Rifampin	10 mg/kg/day once daily.	PO	16 days

Note: Acronyms: IV-Intravenous; PO-Oral Therapy.