Table 1. Clinical characteristics of patients in this study.
| Characteristics | Admitted to ICU (n = 8) | Non-ICU patients (n = 42) | P value |
|---|---|---|---|
| Demographic | |||
| Age, median years (interquartile range) | 63 (57–70) | 49 (30–60) | 0.007 |
| Female | 4 (50) | 24 (57.1) | 0.718 |
| Chronic comorbidities | |||
| Hypertension | 3 (37.5) | 6 (14.3) | 0.144 |
| Chronic heart disease | 0 (0) | 3 (7.1) | 1.000 |
| Chronic lung disease | 0 (0) | 2 (4.8) | 1.000 |
| Chronic liver disease | 1 (12.5) | 0 (0) | 0.160 |
| Chronic kidney disease | 1 (12.5) | 1 (2.4) | 0.297 |
| Diabetes mellitus | 2 (25) | 7 (16.7) | 0.623 |
| No chronic comorbidities | 3 (37.5) | 26 (61.9) | 0.255 |
| Presenting symptoms | |||
| Fever | 7 (87.5) | 27 (64.3) | 0.409 |
| Dyspnea | 4 (50) | 6 (14.3) | 0.041 |
| Cough | 2 (25) | 23 (54.8) | 0.247 |
| Rhinorrhea | 0 (0) | 8 (19.0) | 0.324 |
| Sore throat | 1 (12.5) | 9 (21.4) | 1.000 |
| Diarrhoea | 1 (12.5) | 10 (23.8) | 0.666 |
| Blood tests on admission, median, interquartile range | |||
| Haemoglobin (g/dL) | 12.9 (12.3–13.3) | 13.8 (12.8–14.9) | 0.039 |
| Total white blood cell count (×109/L) | 5.8 (3.6–9.0) | 5.4 (4.3–6.5) | 0.707 |
| Neutrophil count (×109/L) | 4.5 (2.3–8.2) | 3.7 (2.5–4.4)a | 0.488 |
| Lymphocyte count (×109/L) | 0.7 (0.4–0.9) | 1.1 (0.8–1.7)a | 0.004 |
| Platelet count (×109/L) | 158 (137–181) | 191 (163–261) | 0.061 |
| Urea (mmol/L) | 4.5 (3.5–6.0) | 4.3 (2.9–5.0) | 0.397 |
| Creatinine (μmol/L) | 63 (54–92) | 79 (66–93) | 0.194 |
| Alanine aminotransferase (U/L) | 32 (23–41) | 27 (19–45) | 0.668 |
| Severity | |||
| Oxygen supplementation | 8 (100) | 7 (16.7) | <0.001 |
| Death | 1 (12.5) | 0 (0) | 0.160 |
| Geometric mean neutralizing antibody titer (95% confidence interval) | 7280 (1468-36099) | 671 (368-1223) | 0.002 |
aNeutrophil count and lymphocyte count available for 40 patients.