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. 2020 Mar 14;3:41–50. doi: 10.1016/j.crfs.2020.03.001

Fig. 5.

Fig. 5

Bioavailability radar of the flaxseed peptides and inhibitor drugs (captopril and aliskiren), based on physicochemical indices ideal for oral bioavailability. LIPO, Lipophilicity: -0.7 < XLOGP3 < +5; SIZE, Molecular size: 150 g/mol < mol. wt. < 500 g/mol; POLAR, Polarity: 20 Å2 < TPSA <130 Å2; INSOLU, Insolubility: 0 < Log S (ESOL) < 6; INSATU, Insaturation: 0.25 < Fraction Csp3 < 1; FLEX, Flexibility: 0 < Number of rotatable bonds < 9. The coloured zone is the suitable physicochemical space for oral bioavailability.