Table 4.
Hydrogen bonds observed in the best scored docking model of hypotensive flaxseed peptides with ACE.
| ACE residues in H-bonding | Number of H-bonds and their corresponding distance (Å) |
|||||||
|---|---|---|---|---|---|---|---|---|
| IR | KF | LR | LW | SF | TF | YA | Captopril | |
| ALA354:O | 2(2.74,2.68) | 1(2.33) | 2(2.54,2.68) | 2(2.56,2.20) | ||||
| ALA354:HN | 1(2.79) | |||||||
| ASP415:OD1 | 1(2.61) | |||||||
| ASP415:OD2 | 1(2.39) | 1(2.40) | 1(2.67) | |||||
| GLN281:HE21 | 1(2.96) | |||||||
| GLN281:HE22 | 1(2.06) | 1(2.07) | 1(2.16) | 1(2.22) | 1(1.93) | 1(2.11) | ||
| GLU384:OE2 | 1(1.87) | 1(2.33) | 1(2.21) | 1(1.93) | 1(2.89) | |||
| GLU411:OE1 | 2(3.11,2.98) | |||||||
| HIS353:HE2 | 1(2.15) | 1(2.69) | 1(2.16) | 1(2.08) | 1(2.01) | 1(2.11) | 1(2.13) | |
| HIS513:HE2 | 1(2.12) | 1(3.28) | 1(2.16) | 2(2.14,2.72) | 1(2.10) | 1(2.06) | 1(2.22) | |
| HIS513:CE1 | 1(3.65) | 1(3.54) | 1(3.32) | 1(3.41) | 1(3.62) | |||
| LYS511:HZ1 | 1(2.11) | 1(1.79) | 1(2.31) | 1(2.04) | 1(1.78) | |||
| TYR523:OH | 1(1.92) | |||||||
| Total | 4 | 8 | 6 | 8 | 8 | 7 | 6 | 5 |