Fig. 2.

Bee venom significantly induces apoptosis in HPV E6 and E7-positive cervical-cancer cells. (A) Representative data obtained from flow-cytometric analysis of cell-cycle markers after treatment of Caski cells with 5 µg/ml of BV for 0, 12, and 24 h. We fixed cells using 1% PFA and stained DNA with PI as described in Materials and Methods. (B) Caski Cells were treated with BV 5 µg/ml for 24 h and harvested; then DNA was stained with pro-pidium iodide before analysis using FACS.