TABLE 3.
Accuracy of HLA imputation of the five genes where a candidate allele was identified by HTS in the discovery cohort.
| Gene | Imputation accuracy |
| HLA-B | 96.4% (133/138) |
| HLA-C | 94.9% (131/138) |
| HLA-DQA1 | 97.1% (134/138) |
| HLA-DQB1 | 98.6% (136/138) |
| HLA-DRB1 | 88.4% (122/138) |
Accuracies were determined by comparing the typing results of the discovery subset, i.e., the samples for which a typing result by HTS was available, to those obtained by imputation. Number in brackets indicate the number of correctly imputed alleles and the total number of alleles imputed for each gene.