Figure 2.

Representative profiles of follicle growth and reproductive hormone concentrations during an anovulatory interval in women with PCOS-Anov (n = 3) and an interovulatory interval in controls (n = 1). Profiles represent women at the mild (A), moderate (B), and severe ends (C) of the spectrum of antral follicle development in PCOS-Anov, alongside a typical control (D). Each uniquely identified follicle is represented by a different gray-scale line. All follicles that grew to ≥7 mm could be individually tracked over time using the Identity Method. Asterisks indicate ovulatory follicles. Abbreviations: E2, estradiol; FP, follicular phase; FSH, follicle-stimulating hormone; IOI, interovulatory interval; LH, luteinizing hormone; LP, luteal phase; M, menses; P4, progesterone.