Table 4.
Evaluation of Selection and Sporadic Ovulation in Women with PCOS
| Parameter | PCOS-Anov (n = 12) | PCOS-Ov (n = 14) | Control (n = 12) | P Value |
|---|---|---|---|---|
| Characteristics of anovulatory DFs | ||||
| Incidence, n (%)† | 3 / 12 (25.0) | 1 / 14 (7.1) | 1 / 12 (8.3) | NA |
| Diameter on day of selection, mm | 9 ± 1 (9, 10) | NA | 11 | NA |
| Maximum diameter, mm | 10 ± 0 (10) | 14 | 11 | NA |
| Characteristics of ovulatory DFs | ||||
| Incidence, n (%)† | 0 / 12 (0) | 14 / 14 (100) | 12 / 12 (100) | NA |
| Diameter on day of selection, mm | NA | 11 ± 2 (9, 15)$ | 12 ± 2 (9, 15) | 0.54 |
| Maximum diameter, mm | NA | 19 ± 2 (16, 23)ǂ | 19 ± 2 (17, 23) | 0.83 |
| Emergence to ovulation | ||||
| Growth phase, d | NA | 14 ± 3 (11, 20)ǂ | 14 ± 2 (12, 17) | 0.77 |
| Growth rate, mm/d | NA | 1.08 ± 0.26 (0.76, 1.64)ǂ | 1.08 ± 0.16 (0.82, 1.25) | 0.98 |
| Selection to ovulation | ||||
| Growth phase, d | NA | 7 ± 3 (3, 15)$ | 6 ± 2 (4, 9) | 0.66 |
| Growth rate, mm/d | NA | 1.25 ± 0.42 (0.67, 2.00)$ | 1.26 ± 0.20 (1.00, 1.71) | 0.94 |
| Endocrine characteristics | ||||
| Follicular phase | ||||
| Mean LH, mIU/mL | NR | 13.1 ± 3.8 (7.2, 19.3) | 9.8 ± 2.5 (6.0, 13.9) | 0.02 |
| Mean FSH, mIU/mL | NR | 6.0 ± 1.5 (2.8, 8.1) | 7.8 ± 2.5 (4.3, 12.8) | 0.05 |
| Mean E2, pg/mL | NR | 101.2 ± 23.9 (64.1, 142.5) | 112.6 ± 45.0 (53.5, 204.2) | 0.45 |
| Maximum E2, pg/mL | NR | 255.6 ± 96.7 (121.0, 500.0) | 276.5 ± 88.7 (150.0, 458.0) | 0.50 |
| Luteal phase | ||||
| Mean LH, mIU/mL | NR | 6.2 ± 3.3 (2.8, 12.1) | 6.1 ± 2.8 (2.6, 12.8) | 0.95 |
| Mean FSH, mIU/mL | NR | 2.8 ± 1.2 (1.9, 4.9) | 4.9 ± 2.0 (2.6, 9.1) | <0.01 |
| Mean E2, pg/mL | NR | 122.5 ± 49.7 (67.6, 200.3) | 131.0 ± 25.3 (92.9, 177.7) | 0.67 |
| Mean P4, ng/mL | NR | 4.8 ± 1.4 (3.3, 7.8) | 8.6 ± 3.9 (4.2, 17.9) | <0.01 |
| Maximum P4, ng/mL | NR | 7.8 ± 2.4 (5.2, 13.1) | 15.2 ± 6.5 (7.3, 28.5) | <0.01 |
Data are presented as mean ± standard deviation (minimum, maximum).
Abbreviations: DF, dominant follicle; E2, estradiol; FSH, follicle-stimulating hormone; LH, luteinizing hormone; NA, not available or estimable; NR, reported; P4, progesterone.
†This category includes data obtained during the anovulatory interval or follicular phase in women with PCOS-Anov and PCOS-Ov, respectively. $Data were available for 13 / 15 ovulatory follicles. ǂData were available for 12 / 15 ovulatory follicles.