Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 28;57(4):956–966. doi: 10.3892/ijo.2020.5104

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Ng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Suppression of TMEM47 reduces cisplatin chemoresistance of cisplatin-resistant HCC cells. (A) Reverse transcription-PCR analysis of TMEM47 mRNA MHCC97L/CisR-control and MHCC97L/CisR-shTMEM47 cell lines. (B) MTT assay of MHCC97L/CisR-control and MHCC97L/CisR-shTMEM47 cells under cisplatin treatment. (C) Colony formation assay of MHCC97L/CisR-control and MHCC97L/CisR-shTMEM47 cells under cisplatin treatment. (D) In vivo subcutaneous tumor model in nude mice injected with MHCC97L/CisR-control and MHCC97L/CisR-shTMEM47 cells. ^*P<0.05 and ^**P<0.01. TMEM47, transmembrane protein 47; HCC, hepatocellular carcinoma; shTMEM47, short hairpin RNA targeting TMEM47.