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Suppression of TMEM47 enhances the sensitivity of cisplatin-resistant cell lines to cisplatin via increasing apoptosis and affecting the expression of drug-associated genes. (A) Apoptosis assay of MHCC97L/CisR-control and MHCC97L/CisR-shTMEM47 cells under cisplatin treatment. (B) Caspase 3/7 analysis of MHCC97L/CisR-control and MHCC97L/CisR-shTMEM47 cells under cisplatin treatment. *P<0.05 and **P<0.01. TMEM47, transmembrane protein 47; shTMEM47, short hairpin RNA targeting TMEM47.
