Table 1.
Descriptive statistics of the whole sample
| Controls | Cases | p-Value | |
|---|---|---|---|
| N | 2167 | 853 | |
| Age mean (SD) | 34.89 (12.41) | 37.43 (11.64) | < 0.001 |
| Sex, N (%) female | 1201 (55.4) | 516 (60.5) | 0.013 |
| Diagnosis, N (%) | |||
| BD-I | - | 582 (68.63) | |
| BD-II | - | 234 (27.59) | |
| BD-NOS | - | 13 (1.53) | |
| SZA | - | 19 (2.24) | |
| Treatment at the time of scanning, N (%) | |||
| Li | 265 (33.5) | ||
| AED | - | 339 (43.1) | |
| FGA | - | 32 (4.1) | |
| SGA | - | 313 (39.9) | |
| AD | - | 281 (35.5) | |
| Mood state, N (%) | |||
| Euthymic | - | 475 (75.5) | |
| Depressed | - | 131 (20.8) | |
| Manic | - | 11 (1.7) | |
| Hypomanic | - | 9 (1.4) | |
| Mixed | - | 3 (0.5) | |
| Age of onset mean (SD) | - | 22.36 (9.08) | |
| Duration of illness mean (SD) | - | 14.64 (10.45) | |
| History of psychosis, N (%) | - | 372 (61.1) | |
AD antidepressants, AED antiepileptics, BD-I bipolar I disorder, BD-II bipolar II disorder, BD-NOS bipolar disorder not otherwise specified, FGA first-generation antipsychotics, Li lithium, SD standard deviation, SGA second-generation antipsychotics, SZA schizoaffective disorder