Fig. 7.

Anorectic response to a peripheral leptin injection. 24-h food intake in response to an intraperitoneal saline or leptin (2.5 mg/kg) injection in sedentary (SED) and exercised (EX) male and female Wistar rats. Data are presented as a percentage of average energy intake overall (males) or on equivalent estrous cycle days (females) to control for differences in the estrous cycle across the leptin and control injection days. All groups saw a similar and significant decrease in food intake following the leptin injection as compared with saline. P < 0.001, main effect of injection.