. 2010 Jun 17;319(2):R148–R155. doi: 10.1152/ajpregu.00057.2020

Table 1.

Effects of chronic hypoxia on the activities of key enzymes of energy metabolism in various tissues of naked mole-rats

	PK		LDH		CS		CPT		HOAD
	/g_tissue	/µg_protein	/g_tissue	/µg_protein	/g_tissue	/µg_protein	/g_tissue	/µg_protein	/g_tissue	/µg_protein
Brain	−89%^***	−97%^***	NS	−73%^***	−25%^**	−76%^***	−94%^*	−98%^*	NS	NS
Heart	−93%^***	−90%^***	NS	NS	+94%^***	+115%^***	NS	NS	NS	NS
Liver	−99%^***	−99%^***	−73%^***	−82%^***	−36%^**	−57%^**	−89%^**	−98%^**	−69%^***	−80%^***
Muscle	−61%^**	−79%^**	−62%^***	−80%^***	−59%^***	−78%^***	−96%^***	−98%^**	−86%^**	−93%^***
Kidney	−90%^**	−96%^**	+81%^**	NS	NS	−56%^***	NS	NS	NS	NS

Effects of chronic hypoxia on the activities of key enzymes of energy metabolism (standardized either per gram tissue or per gram protein) in various tissues of naked mole-rats (n = 12 mole-rats in normoxia and n = 9 mole-rats in hypoxia) are shown. No effect of hypoxia is indicated by NS (P > 0.05). Significant effects of hypoxia are indicated as

P < 0.05,

^**

P < 0.01, and

^***

P < 0.001, presented as percent differences between treatments.