Table 2.

Relative effects of chronic hypoxia on the membrane phospholipids of naked mole-rat tissues

	DBI	PL/g	SFA	MUFA	PUFA
Brain	NS	+18%**	NS	NS	NS
Heart	NS	NS	NS	NS	NS
Liver	−23%*	+50%**	+24%*	−43%***	−12%*
Muscle	+22%*	−28%***	−27%*	NS	+11%*
Kidney	NS	NS	NS	NS	−5%*

Relative effects of chronic hypoxia on the membrane phospholipids of naked mole-rat tissues (n = 12 mole-rats in normoxia and n = 9 mole-rats in hypoxia). Double bond index (DBI), phospholipid/g_tissue (PL/g), saturated fatty acids (SFA), monounsaturated fatty acids (MUFA), and polyunsaturated fatty acids (PUFA) are indicated separately. Absolute concentrations of PL and FAs in moles per gram tissue (Supplemental Table 1; see https://doi.org/10.6084/m9.figshare.11988768.v2) were used to calculate the percent changes presented. No effect of hypoxia is indicated by NS (P > 0.05). Significant effects of hypoxia are indicated as

^*P < 0.05,

^**P < 0.01, and

^***P < 0.001.