Table 3.
Control | Tailless | Control | Tailless | |
---|---|---|---|---|
22°C | 30°C | |||
n of mice | 5 | 6 | 5 | 6 |
n of data points in data set | 585 | 702 | 725 | 870 |
TlcEE, °C | 28.92 ± 0.19 | 28.43 ± 0.15 | 28.60 ± 0.01 | 28.19 ± 0.20 |
Tbinc, °C | 28.74 ± 0.33 | 28.69 ± 0.18 | 27.69 ± 0.19 | 27.92 ± 0.01 |
Tlccond, °C | 28.70 ± 0.21 | 27.95 ± 0.22 | 28.19 ± 0.22 | 28.00 ± 0.02 |
TEE, at TlcEE, kcal/h | 0.221 ± 0.004 | 0.233 ± 0.008 | 0.230 ± 0.008 | 0.230 ± 0.008 |
Cond, <Tlccond, kcal·h−1·Δ°C−1 | 0.0335 ± 0.0012 | 0.0334 ± 0.0010 | 0.0310 ± 0.0022 | 0.0290 ± 0.0014 |
Tb, <Tbinc, °C | 35.27 ± 0.08 | 35.31 ± 0.11 | 35.15 ± 0.08 | 35.30 ± 0.16 |
defended Tb, °C | 36.20 ± 0.47 | 35.43 ± 0.44 | 37.86 ± 0.41 | 36.85 ± 0.52 |
TEE Slope, <TlcEE, kcal·h−1·°C−1 | −0.0304 ± 0.0013 | −0.0334 ± 0.0013 | −0.0248 ± 0.0006 | −0.0266 ± 0.0009 |
Tb Slope, >Tbinc <Tb_R, °C Tb/°C | 0.256 ± 0.030 | 0.391 ± 0.023 | 0.272 ± 0.021 | 0.345 ± 0.024 |
Cond Slope, >Tlccond <Cond_R, kcal·h−1·Δ°C−1·°C−1 | 0.0063 ± 0.0004 | 0.0044 ± 0.0003 | 0.0061 ± 0.0003 | 0.0055 ± 0.0001 |
TEE_R, °C | 33.78 ± 0.37 | 33.68 ± 0.02 | 35.24 ± 0.39 | 34.50 ± 0.34 |
Tb_R, °C | 32.85 ± 0.16 | 33.21 ± 0.23 | 33.31 ± 0.15 | 33.29 ± 0.19 |
Cond_R, °C | 33.47 ± 0.24 | 33.36 ± 0.13 | 35.83 ± 0.11 | 35.33 ± 0.06 |
TEE Slope, >TEE_R, kcal·h−1·°C−1 | 0.0275 ± 0.0058 | 0.0299 ± 0.0027 | 0.0181 ± 0.0037 | 0.0178 ± 0.0027 |
Tb Slope, >Tb_R, °C Tb/°C | 0.841 ± 0.033 | 0.776 ± 0.035 | 0.728 ± 0.049 | 0.684 ± 0.029 |
Cond Slope, >Cond_R, kcal·h−1·Δ°C−1·°C−1 | 0.0131 ± 0.0007 | 0.0141 ± 0.0006 | 0.0296 ± 0.0014 | 0.0267 ± 0.0006 |
Body wt, g | 29.78 ± 1.37 | 27.97 ± 1.00 | 31.32 ± 1.44 | 30.47 ± 0.84 |
Age, wk | 33 | 33 | 28 | 28 |
Data are means ± SE (see materials and methods and Fig. 2). Parameters were calculated from analysis of total energy expenditure (TEE), body temperature (Tb), and conductance as a function of ambient temperature (Ta) by mixed model segmented linear regression. Cond Slope, >Cond_R, conductance vs. Ta slope for Ta >Cond_R; Cond Slope, >Tlccond <Cond_R, conductance slope in the region >Tlccond and <Cond_R; Cond, <Tlc, mean conductance at Ta <Tlccond; Cond_R, second breakpoint of the conductance vs. Ta graph; defended Tb, X intercept of TEE vs. Ta line (using only Ta <TlcEE); Tb Slope, >Tb_R, Tb vs. Ta slope for Ta >Tb_R; Tb Slope, >Tbinc <Tb_R, Tb slope in the region >Tbinc and <Tb_R; Tb, <Tbinc, mean Tb at Ta < Tbinc; Tb_R, second breakpoint of the Tb vs. Ta graph, where Tb starts to steeply rise with Ta; Tbinc, Ta above which the Tb first increases; TEE at TlcEE, mean TEE at Ta = TlcEE; TEE Slope > TEE_R, TEE vs. Ta slope for Ta >TEE_R; TEE Slope, <TlcEE, TEE vs. Ta slope for Ta <TlcEE; TEE_R, breakpoint of the TEE vs. Ta graph, where TEE starts to rise with Ta; TlcEE, lower critical temperature, the (first) breakpoint of the TEE vs. Ta graph; Tlccond, lower critical temperature, the (first) breakpoint of the conductance vs. Ta graph.