Fig. 2.
Shunt- and transverse aortic constriction (TAC)-induced cardiac remodeling. A: left ventricular weight-to-tibia length ratio as a marker of hypertrophy (n = 5–6 mice/group). B: relative wall thickness. C: left ventricular ejection fraction. ShamS, control group for Shunt; ShamT, control group for TAC. n = 8–14 mice/group. Data are presented as means ± SE. **P < 0.01 between Shunt/TAC and the respective Sham control. ns, Not significant by unpaired Student’s t test. Gaps in the x-axis indicate that Shunt and TAC experiments were performed and analyzed separately.