Fig. 3.

Percent ¹³C enrichment of metabolites in the heart following in vivo infusion of [U-¹³C]glucose in Shunt and transverse aortic constriction (TAC). A: lactate; B: succinate; C: glutamate; D: glutamine; E: alanine; F: glycine; G: aspartate; and H: glucose. Sham_S, control group for Shunt; Sham_T, control group for TAC. n = 4–5 mice/group. Data are presented as means ± SE. *P < 0.05 and **P < 0.01 between Shunt/TAC and the respective Sham control. ns, Not significant by unpaired Student’s t test. Gaps in the x-axis indicate that Shunt and TAC experiments were performed and analyzed separately.