Table 1.

Echocardiographic measurements following 2 wk of Shunt and TAC

	ShamS	Shunt	ShamT	TAC
n	8	11	8	14
Heart rate, beats/min	472 ± 16.9	505 ± 10.7	466 ± 13.1	504 ± 19.0
LVIDd, mm	4.1 ± 0.02	4.7 ± 0.03**	4.1 ± 0.04	4.2 ± 0.07
LVIDs, mm	2.9 ± 0.02	3.4 ± 0.05**	3.1 ± 0.06	3.5 ± 0.10**
LVVd, µl	74.2 ± 1.0	104.3 ± 1.9**	74.4 ± 2.1	81.1 ± 3.3
LVVs, µl	33.4 ± 0.70	48.5 ± 1.7**	36.8 ± 2.1	51.8 ± 3.7**
Septum, mm	0.71 ± 0.01	0.74 ± 0.01	0.68 ± 0.01	0.87 ± 0.01**
Posterior wall, mm	0.61 ± 0.01	0.69 ± 0.01**	0.62 ± 0.01	0.81 ± 0.02**
LV mass, mg	73.3 ± 0.82	107.6 ± 2.1**	75.0 ± 3.5	108.8 ± 4.5**
RWT	0.32 ± 0.01	0.30 ± 0.01**	0.32 ± 0.01	0.40 ± 0.01**
SV, µl	40.9 ± 0.88	55.8 ± 1.7**	37.6 ± 0.75	29.6 ± 1.5**
EF, %	55.1 ± 0.86	53.6 ± 1.4	50.9 ± 1.5	37.3 ± 2.4**
FS, %	28.3 ± 0.55	27.7 ± 0.90	25.7 ± 0.92	18.0 ± 1.3**

Values are means ± SE; n, number of mice. TAC, transverse aortic constriction; Sham_S, control group for Shunt; Sham_T, control group for TAC; LVID_d and LVID_s, left ventricular inner diameter during diastole (d) or systole (s); LVV_d and LVV_s, left ventricular volume during diastole (d) or systole (s); LV, left ventricular; RWT, relative wall thickness; SV, stroke volume; EF, ejection fraction; FS, fractional shortening.

^**P < 0.01 between Shunt/TAC and respective control group by unpaired Student’s t test.