Fig. 7.

Representative factors found to be significantly elevated in plasma of 1-wk wk left ventricular pressure overload (LVPO) mice that were not elevated in plasma of mice with silica-instilled pulmonary fibrosis (PF). CC ligand-21 (CCL-21) remained elevated in plasma of mice with 4 wk of pressure overlaod (PO). Although CCL-21 was also elevated in 1 wk LVPO myocardium (B), granulocyte macrophage-colony stimulating factor (GM-CSF) was not increased in hearts at 1 wk of LVPO (data not shown; A). *P < 0.05, LVPO vs. control; #P < 0.05, LVPO vs. corresponding sham.