Table 1.
Gravimetric measurements (mass)
| n | Body, g | Heart, mg | Left Ventricle, mg | Lung, mg | Kidney, mg | LV/Body, mg/g | Lung/Body, mg/g | Kidney/Body, mg/g | |
|---|---|---|---|---|---|---|---|---|---|
| Control | 16 | 26 ± 1 | 129 ± 6 | 87 ± 4 | 141 ± 4 | 157 ± 8 | 3.3 ± 0.1 | 5.5 ± 0.1 | 6.0 ± 0.1 |
| Sham | 16 | 24 ± 1 | 128 ± 6 | 87 ± 4 | 134 ± 4 | 153 ± 7 | 3.6 ± 0.1 | 5.7 ± 0.1 | 6.3 ± 0.2 |
| LVPO, 1 wk | 9 | 26 ± 1 | 184 ± 16*# | 137 ± 12*,# | 229 ± 35*# | 137 ± 6 | 6.0 ± 0.6*,# | 10.2 ± 1.8*,# | 5.3 ± 0.2*,# |
| LVPO, 4 wk | 8 | 24 ± 1 | 248 ± 15*# | 175 ± 9*,# | 372 ± 52*# | 138 ± 3 | 7.4 ± 0.5*,# | 15.7 ± 2.3*,# | 5.8 ± 0.2 |
| Silica | 10 | 33 ± 1*# | 152 ± 6 | 105 ± 4*,# | 248 ± 22*# | 183 ± 7*# | 3.1 ± 01. | 7.3 ± 0.5*,# | 5.5 ± 0.1# |
Values are means ± SE. LV, left ventricle; LVPO, left ventricular pressure overload.
*
P < 0.05 vs. control;
#
P < 0.05 vs. sham.