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Sepsis-induced increases in calpain (A), caspase (B), and 20S proteasome proteolytic activity (C). MitoTEMPOL administration blocked each of these cecal ligation puncture (CLP)-mediated effects. Data were obtained from n = 4 animals/group. Data are plotted with boxes representing 1 SE; the dark line in the box indicates the mean, and whiskers indicate the minimum and maximum values. *Statistical significance.
